Publications


CONEM collaborates in research and publishes research and review articles in international peer-reviewed journals. The publications are sorted alphabetically by year and title.


Online First / In Press


Altered S100 Calcium-Binding Protein B and Matrix Metallopeptidase 9 as Biomarkers of Mesial Temporal Lobe Epilepsy with Hippocampus Sclerosis
Meguid NA, Samir H, Bjørklund G, Anwar M, Hashish A, Koura F, Chirumbolo S, Hashem S, El-Bana MA, Hashem HS
J Mol Neurosci 2018. Accepted

Association Between Catatonia and Levels of Hair and Serum Trace Elements and Minerals in Autism Spectrum Disorder
Tinkov A, Klyushnik T, Simashkova N, Notova S, Kiyaeva E, Skalnaya A, Skalny A, Bjørklund G, Skalnaya M
Biomed Pharmacother 2018. Accepted

Cancer-Associated Cachexia, Reactive Oxygen Species, and Nutrition Therapy
Bjørklund G, Dadar M, Aaseth J, Chirumbolo S, Pen JJ
Curr Med Chem 2018. doi: 10.2174/0929867325666180629123817

Chronic fatigue syndrome (CFS): suggestions for a nutritional treatment in the therapeutic approach
Bjørklund G, Dadar M, Pen JJ, Chirumbolo S, Aaseth J
Biomed Pharmacother 2018. Accepted

Diagnostic and Severity-Tracking Biomarkers for Autism Spectrum Disorder
Bjørklund G, Meguid NA, El-Ansary A, El-Bana MA, Dadar M, Aaseth J, Hemimi M, Osredkar J, Chirumbolo S
J Mol Neurosci 2018

Evaluation of Childhood Vaccine Refusal and Hesitancy Intentions in Turkey: Correspondence
Chirumbolo S, Bjørklund G
Indian J Pediatr 2018. doi: 10.1007/s12098-018-2772-3

High Content of Lead is Associated with the Softness of Drinking Water and Raised Cardiovascular Morbidity: A Review
Bjørklund G, Dadar M, Chirumbolo S, Aaseth J
Biol Trace Elem Res 2018. Accepted (IF 2.399)

*How Important is Tryptophan in Human Health?
Kałużna-Czaplińska J, Gątarek P, Salvatore Chirumbolo, Chartrand MS, Bjørklund G
Crit Rev Food Sci Nutr 2017. Accepted (IF 6.077)

Insights on Melatonin as a Major Pharmacological Target in Cancer Prevention: What’s New?
Bjørklund G, Rajib SA, Saffoon N, Pen JJ, Chirumbolo S
Curr Med Chem. Accepted 23.04.2018

Matrix Assisted Laser Desorption/Ionization as a New Cancer Diagnostic Tool 
Hosnedlova B, Kepinska M, Ruttkay-Nedecky B, Fernandez C, Parak P, Milnerowicz H, Sochor J, Bjørklund G, Kizek R
Reference Module in Biomedical Research 2018. doi: 10.1016/B978-0-12-801238-3.10887-6.

*Molecular Imaging and Cancer Gene Therapy
Saadatpour Z, Bjørklund G, Chirumbolo S, Alimohammadi M, Ehsani H, Ebrahiminejad H, Pourghadamyari H, Mirzaei HR, Sahebkar A, Mirzaei H, Keshavarzi M
Cancer Gene Ther. 2016 Nov 18. doi:10.1038/cgt.2016.62. PubMed PMID: 27857058 (IF 2.532)

Selenium and Autism Spectrum Disorder
Skalny AV, Skalnaya MG, Bjørklund G, Gritsenko VA, Aaseth J, Tinkov AA
In: Michalke B (ed) Selenium. Molecular and Integrative Toxicology. Basel: Springer, 2018.  https://doi.org/10.1007/978-3-319-95390-8_10

Selenium, Selenoprotein P, and Alzheimer’s disease: is there a link?
Solovyev N, Drobyshev E, Bjørklund G, Dubrovskiy Y, Lysiuk R, Rayman M
Free Radic Biol Med. Accepted 22.2.2018

Therapeutic Effects of Probiotics on Neurotoxicity Induced by Clindamycin and Propionic Acid in Juvenile Hamsters
Al-Orf N, El-Ansary A, Bjørklund G, Moubaye N, Shafi Bhat R, Ben Bacha A
Metabol Brain Dis 2018.  In press

The Role of Matrix Gla Protein (MGP) in Vascular Calcification: An Update on Mechanisms and Challenges
Bjørklund G, Svanberg E, Dadar M, Card DJ, Harrington DJ, Aaseth J
Curr Med Chem. Accepted 16.07.2018


Publications 2019


Mercury in Dental Amalgams: A Great Concern for Clinical Toxicology in Developing Countries?
Bjørklund G, Lindh U, Aaseth J, Mutter J, Chirumbolo S
J Trace Elem Med Biol 2019;51:9-11. PubMed PMID:


Publications 2018


Agathisflavone and GABAA receptors in the biflavone-mediated action on rat primary cortical neurons
Chirumbolo S, Bjørklund G
Neurotoxicology 2018;66:43-44. PubMed PMID: 29530473 (IF 3.100)

Associations Between Depression, Anxiety and Medication Adherence Among Patients with Arterial Hypertension: Comparison Between Persons Exposed and Non-Exposed to Radiation from the Semipalatinsk Nuclear Test Site
Dyussenova L, Pivina L, Semenova Y, Bjørklund G, Glushkova N, Chirumbolo S, Belikhina T
J Environ Radioact 2018;195:33-39. doi: 10.1016/j.jenvrad.2018.09.016. PubMed PMID: 30241015

A study of ghrelin and leptin levels and their relationship to metabolic profiles in obese and lean Saudi women with polycystic ovary syndrome (PCOS)
Daghestani MH, Daghestani M, Daghistani M, El-Mazny A, Bjørklund G, Chirumbolo S, Al Saggaf SH, Warsy A
Lipids Health Dis. 2018 Aug 21;17(1):195. doi: 10.1186/s12944-018-0839-9. PubMed PMID: 29990849

A Systematic Review and Meta-Analysis of Metal Concentrations in Canned Tuna Fish in Iran and Human Health Risk Assessment
Rahmani J, Fakhri Y, Miri A, Shahsavani A, Bahmani Z, Urbina MA, Chirumbolo S, Keramati H, Moradi B, Bay A, Bjørklund G
Food Chem Toxicol 2018;118:753-765. PubMed PMID: 29913231

Bias and Misleading Concepts in an Arnica Research Study. Comments to Improve Experimental Homeopathy
Chirumbolo S, Bjørklund G
J Ayurveda Integr Med 2018;9:75-80. PubMed PMID: 29496319

Brief Challenges on Medicinal Plants: An Eye-Opening Look at Aging-Related Disorders
Bjørklund G, Dadar M, Martins N, Chirumbolo S, Goh BH, Smetanina K, Lysiuk R
Basic Clin Pharmacol Toxicol. 2018 Jun;122(6):539-558. PubMed PMID: 29369521

Cadmium and Atherosclerosis: A Review of Toxicological Mechanisms and a Meta-analysis of Epidemiologic Studies
Tinkov AA, Filippini T, Ajsuvakova OP, Aaseth J, Bjørklund G, Skalnaya MG, Gatiatulina ER, Popova EV, Nemereshina ON, Huang PT, Vinceti M, Skalny AV
Environ Res 2018;162:240-260. PubMed PMID: 29358116 (IF 3.835)

Cerebral Hypoperfusion in Autism Spectrum Disorder
Bjørklund G, Kern J, Urbina M, Saad K, El-Houfey A, Geier D, Chirumbolo S, Geier M, Mehta J, Aaseth J
Acta Neurobiol Exp (Wars) 2018;78:21-29. PubMed PMID: 29694338 (IF 1.207)

Comments on Schocker et al.
Chirumbolo S, Bjørklund G, Vella A
Pediatr Allergy Immunol 2018;29:459-460. PubMed PMID: 29369413

Concentrations of Arsenic and Lead in Rice (Oryza Sativa L.) in Iran: A Systematic Review and Carcinogenic Risk Assessment
Fakhri Y, Bjørklund G, Bandpei AM, Chirumbolo S, Keramati H, Hosseini Pouya R, Asadi A, Amanidaz N, Sarafraz M, Sheikhmohammad A, Alipour M, Baninameh Z, Mohseni SM, Sarkhosh M, Ghasemi SM
Food Chem Toxicol 2018;113:267-277. PubMed PMID: 29341878 (IF 3.778)

Delayed-Type Hypersensitivity to Metals in Connective Tissue Diseases and Fibromyalgia
Bjørklund G, Dadar M, Aaseth J
Environ Res 2018;161:573-579. PubMed PMID: 29245125 (IF 3.835)

Effects of Arsenic Toxicity beyond Epigenetic Modifications
Bjørklund G, Aaseth J, Chirumbolo S, Urbina MA, Uddin R
Environ Geochem Health 2018;40:955-965. PubMed PMID: 28484874 (IF 2.079)

Fibromyalgia and Nutrition: Therapeutic Possibilities?
Bjørklund G, Dadar M, Chirumbolo S, Aaseth J
Biomed Pharmacother 2018;103:531-538. PubMed PMID: 29677539 (IF 2.759)

Homeopathic Dilutions, Hahnemann, and the Solvent Issue: Must We Address Ethanol as a “Homeopathic” or a “Chemical” Issue?
Chirumbolo S, Bjørklund G
Homeopathy 2018;107:40-44. PubMed PMID: 29528477 (IF 1.160)

Impaired Lipid Metabolism Markers to Assess the Risk of Neuroinflammation in Autism Spectrum Disorder
Qasem H, Al-Ayadhi L, Bjørklund G, Chirumbolo S, El-Ansary A
Metab Brain Dis 2018;33:1141-1153. PubMed PMID: 29569150

Increased Prevalence of Essential Hypertension in Areas Previously Exposed to Fallout Due to Nuclear Weapons Testing at the Semipalatinsk Test Site, Kazakhstan
Markabayeva A, Bauer S, Pivina L, Bjørklund G, Chirumbolo S, Kerimkulova A, Semenova Y, Belikhina T
Environ Res 2018;167:129-135. PubMed PMID: 30014894

In the Search for Reliable Biomarkers for the Early Diagnosis of Autism Spectrum Disorder: the Role of Vitamin D
El-Ansary A, Cannell JJ, Bjørklund G, Bhat RS, Al Dbass AM, Alfawaz HA, Chirumbolo S, Al-Ayadhi L
Metab Brain Dis 2018;33:917-931. PubMed PMID: 29497932

Mast Cell Activation Test Versus Basophil Activation Test and Related Competing Issues
Chirumbolo S, Bjørklund G, Vella A
J Allergy Clin Immunol 2018;142:1018-1019. doi: 10.1016/j.jaci.2018.06.020. PubMed PMID: 30055831

Mercury Exposure and Health Impacts in Dental Personnel
Aaseth J, Hilt B, Bjørklund G
Environ Res 2018;164:65-69. PubMed PMID: 29482185 (IF 3.835)

Metabolism-Associated Markers and Childhood Autism Rating Scales (CARS) as a Measure of Autism Severity
El-Ansary A, Bjørklund G, Khemakhem AM, Al-Ayadhi L, Chirumbolo S, Bacha AB
J Mol Neurosci 2018;65:265-276. doi: 10.1007/s12031-018-1091-5. PubMed PMID: 29931502

Metals and Parkinson’s disease: Mechanisms and Biochemical Processes
Bjørklund G, Stejskal V, Urbina MA, Dadar M, Chirumbolo S, Mutter J
Curr Med Chem 2018;25:2198-2214. PubMed PMID: 29189118

Nano-Selenium and Its Administration to Selenium-Deficient and Nanomedicine Applications: A Critical Review
Hosnedlova B, Kepinska M, Skalickova S, Fernandez C, Ruttkay-Nedecky B, Peng Q, Baron M, Melcova M, Opatrilova R, Jarmila Zidkova J, Bjørklund G, Sochor J, Kizek R
Int J Nanomedicine 2018;13:2107–2128. PubMed PMID: 29692609 (IF 4.300)

On the Reliability of the CD123-Endowed Basophil Activation Test (BAT) and Its Application in Food Allergy
Chirumbolo S, Bjørklund G, Vella A
Clin Exp Allergy 2018;48:1068-1070. doi: 10.1111/cea.13206. PubMed PMID: 29905025

Plasma Concentrations of the Trace Elements Copper, Zinc and Selenium in Brazilian Children with Autism Spectrum Disorder
Saldanha Tschinkel PF, Bjørklund G, Conón LZZ, Chirumbolo S, Nascimento VA
Biomed Pharmacother 2018;106:605-609. doi: 10.1016/j.biopha.2018.06.174. PubMed PMID: 29990849

Pressure to Publish in the Biomedical Scientific Field: Ethical Conflicts or a Possible Obsessive-Compulsive Disorder?
Chirumbolo S, Bjørklund G
Eur J Intern Med 2018;50:e16-e17. doi: 10.1016/j.ejim.2018.01.012. PubMed PMID: 29329892 (IF 2.960)

Probiotic Treatment Reduces the Autistic-Like Excitation/Inhibition Imbalance in Juvenile Hamsters Induced by Orally Administered Propionic Acid and Clindamycin
El-Ansary A, Bacha AB, Bjørklund G, Al-Orf N, Bhat RS, Moubayed N, Abed K
Metab Brain Dis 2018;33:1155-1164. PubMed PMID: 29582256

Quercetin affecting gelatinases in rat aortas: Some comments
Chirumbolo S, Bjørklund G
Atherosclerosis 2018;275:444-445. doi: 10.1016/j.atherosclerosis.2018.02.033. PubMed PMID: 29582256

Quercetin in collagen-induced arthritis. Some comments
Chirumbolo S, Bjørklund G
Int Immunopharmacol. 2018 Sep;62:335-336. doi: 10.1016/j.intimp.2018.06.003. PubMed PMID: 29970297 (IF 2.956)

Quercetin in the Experimental Liver Fibrosis Induced by Carbon Tetrachloride (CCl4)
Chirumbolo S, Bjørklund G
Int Immunopharmacol 2018;55:254-256. PubMed PMID: 29287251 (IF 2.956)

Randomized-Controlled Trial of Vitamin D Supplementation in Children with Autism Spectrum Disorder
Saad K, Abdel-rahman AA, Elserogy YM, Al-Atram AA, El-Houfey AA, Othman HAK, Bjørklund G, Jia F, Urbina MA, Abo-Elela MGM, Ahmad FA, Abd El-Baseer KA, Ahmed AE, Abdel-Salam AM
J Child Psychol Psychiatry 2018;59:20-29. PubMed PMID: 27868194 (IF 6.615)

Relationship between Absolute and Relative Ratios of Glutamate, Glutamine and GABA and Severity of Autism Spectrum Disorder
Al-Otaish H, Al-Ayadhi L, Bjørklund G, Chirumbolo S, Urbina MA, El-Ansary A
Metab Brain Dis 2018;33:843-854. PubMed PMID: 29397522

Sulforaphane and 5-fluorouracil Synergistically Inducing Autophagy in Breast Cancer: A Possible Role for the Nrf2-Keap1-ARE Signaling?
Chirumbolo S, Bjørklund G
Food Chem Toxicol 2018;112:414-415. PubMed PMID: 29305271 (IF 3.778)

The Contamination and Prevalence of Histamine in Canned Tuna Fish of Iran: A Systematic Review, Meta-Analysis, and Health Risk Assessment
Rahmani J, Miri A, Mohseni-Bandpei A, Fakhri Y, Bjørklund G, Keramati H, Moradi B, Amanidaz N, Shariatifar N, Mousavi Khaneghah A
J Food Prot 2018. In press

The Effect of Vitamin C on Cyprinus Carpio Survival in Water Environment with Chemical Toxicants. Some Comments
Chirumbolo S, Bjørklund G
Aquat Toxicol 2018;197:7-8. PubMed PMID: 29407797 (IF 4.129)

The Purported Kinship Between Melatonin and Quercetin in the Anti-Oxidant Activity Against the LPS-Mediated Cell Damage
Chirumbolo S, Bjørklund G
Food Chem Toxicol 2018;120:588-589. doi: 10.1016/j.fct.2018.08.005. PubMed PMID: 30081044

The Role of Basophils as Innate Immune Regulatory Cells in Allergy and Immunotherapy
Chirumbolo S, Bjørklund G, Sboarina A, Vella A
Hum Vaccin Immunother 2018;14:815-831. PubMed PMID: 29257936 (IF 2.157)

The Role of the Thioredoxin/Thioredoxin Reductase System in Metabolic Syndrome: Towards a Possible Prognostic Marker?
Tinkov AA, Bjørklund G, Skalny AV, Holmgren A, Skalnaya MG, Chirumbolo S, Aaseth J
Cell Mol Life Sci 2018;75:1567-1586. PubMed PMID: 29327078 (IF 5.788)

The Use of Multi-Parametric Biomarker Profiles May Increase the Accuracy of ASD Prediction
Hassan WM, Al-Ayadhi L, Bjørklund G, Alabdali A, Chirumbolo S, El-Ansary A
J Mol Neurosci. 2018;66:85-101. doi: 10.1007/s12031-018-1136-9. PubMed PMID: 30112624

Toxic metal(loid)-based pollutants and their possible role in autism spectrum disorder
Bjørklund G, Tinkov AA, Rahman MM, Dadar M, Yassa HA, Aaseth J, Chirumbolo S, Skalnaya MG, Skalny AV
Environ Res 2018;166:234-250. PubMed PMID: 29902778

Vanillic Acid in Endometrial Carcinoma: A Role for Nitric Oxide?
Chirumbolo S, Bjørklund G
Indian J Clin Biochem 2018;33:239-240. PubMed PMID: 29651219


Publications 2017


Assessment of Gender and Age Effects on Serum and Hair Trace Element Levels in Children with Autism Spectrum Disorder 
Skalny AV, Simashkova NV, Skalnaya AA, Klyushnik TP, Bjørklund G, Skalnaya MG, Tinkov AA
Metab Brain Dis 2017; 32: 1675–1684. PubMed PMID: 28664504

Chrysin and Baicalin in Diabetic Nephropathy
Chirumbolo S, Bjørklund G
Environ Toxicol Pharmacol 2017;51:156-157. PubMed PMID: 28262431 (IF 2.187)

Concerns about Environmental Mercury Toxicity: do we forget something else?
Bjørklund G, Bengtsson U, Chirumbolo S, Kern JK
Environ Res 2017;152:514-516. PubMed PMID: 27616662 (IF 3.835)

Developmental Neurotoxicants and the Vulnerable Male Brain: A Systematic Review of Suspected Neurotoxicants that Disproportionally Affect Males
Kern JK, Geier DA, Homme KG, King PG, Bjørklund G, Chirumbolo S, Geier MR
Acta Neurobiol Exp (Wars) 2017;77:269-296. PubMed PMID:

Dietary Adequacy of Egyptian Children with Autism Spectrum Disorder Compared to Healthy Developing Children
Meguid NA, Anwar M, Bjørklund G, Hashish A, Chirumbolo S, Hemimi M, Sultan E
Metab Brain Dis 2017;32:607-615. PubMed PMID: 28074329 (IF 2.603)

Extended Consensus on Blood Pressure Variability beyond Blood Pressure for Management of Hypertension
Singh RB, Hristova K, Bjørklund G, Fedacko J, Chirumbolo S, Pella D
J Am Soc Hypertens 2017;11:6-9. PubMed PMID: 28040405 (IF 2.656)

Flavonoids as Detoxifying and Pro-Survival Agents: What’s New?
Bjørklund G, Dadar M, Chirumbolo S, Lysiuk R
Food Chem Toxicol 2017;110:240-250. PubMed PMID: 29079495 (IF 3.778)

Hair Toxic and Essential Trace Elements in Children with Autism Spectrum Disorder
Skalny AV, Klyushnik TP, Simashkova NV, Grabeklis AR, Bjørklund G, Skalnaya MG, Nikonorov AA, Tinkov AA
Metab Brain Dis 2017;32:195-202. PubMed PMID: 27581303 (IF 2.603)

Histone Deacetylase Inhibitors, Thimerosal, and Autism Spectrum Disorder
Bjørklund G, Chirumbolo S, Geier DA, Kern JK, Geier MR
Environ Res 2017;156:843–844. PubMed PMID: 28410622 (IF 3.835)

Homeopathic Arnica from Boiron and Post-Operative Bleeding in Mastectomized Women in Milan: Statistical Flaws and Bias to be Addressed
Chirumbolo S, Bjørklund G
J Tradit Complement Med 2017;8:1-3. PubMed PMID: 29321982

Homeopathic Potencies of Arnica Montana L. Change Gene Expression in a THP-1 Cell Line in Vitro Model: the Role of Ethanol as a Possible Confounder and Statistical Bias
Chirumbolo S, Bjørklund G
J Integr Med 2017;15:255-264.PubMed PMID: 28659229

Imaging Techniques: New Avenues in Cancer Gene and Cell Therapy
Saadatpour Z, Rezaei A, Ebrahimnejad H, Baghaie B, Bjørklund G, Chartrand M, Sahebkar A, Morovati H, Mirzaei HR, Mirzaei H
Cancer Gene Ther 2017;24:1-5. PubMed PMID: 27834357 (IF 2.532)

Interactions of Iron with Manganese, Zinc, Chromium, and Selenium as Related to Prophylaxis and Treatment of Iron Deficiency
Bjørklund G, Aaseth J, Skalny AV, Suliburska J, Skalnaya MG, Nikonorov AA, Tinkov AA
J Trace Elem Med Biol 2017;41:41-53. PubMed PMID: (IF 2.550)

Is there a relationship between intestinal microbiota, dietary compounds, and obesity?
Kałużna-Czaplińska J, Gątarek P, Chartrand MS, Dadar M, Bjørklund G
Trends Food Sci Technol 2017;70:105-113 (IF 5.191)

Manganese Exposure and Neurotoxic Effects in Children
Bjørklund G, Chartrand MS, Aaseth J
Environ Res 2017;155:380-384. PubMed PMID: 28282629  (IF 3.835)

May Traffic Air Pollution be Involved in Autism Spectrum Disorder?
Chirumbolo S, Bjørklund G, Urbina MA
Environ Res 2017;154:57-59. PubMed PMID: 28038434 (IF 3.835)

Metal Chelators and Neurotoxicity: Lead, Mercury, and Arsenic
Bjørklund G, Mutter J, Aaseth J
Arch Toxicol 2017;91:3787-3797. PubMed PMID: 29063135

Molecular and Physiological Roles of Estrogen Receptor
Al-Khatib AJ, Ali Shotar A, Bjørklund G
J Pharm Pharmaceutics 2017;4(1): 1- 9. doi:10.15436/2377-1313.17.021

Molecular Interaction between Mercury and Selenium in Neurotoxicity
Bjørklund G, Aaseth J, Ajsuvakova OP, Nikonorov AA, Skalny AV, Skalnaya MG, Tinkov AA
Coord Chem Rev 2017;332:30-37 (IF 12.994)

PERM Hypothesis: The Fundamental Machinery Able to Elucidate the Role of Xenobiotics and Hormesis in Cell Survival and Homeostasis
Chirumbolo S, Bjørklund G
Int J Mol Sci 2017;18:165. doi:10.3390/ijms18010165. PubMed PMID: 28098843 (IF 3.257)

Plasma alpha-L-fucosidase Activity in Chronic Inflammation and Autoimmune Disorders in a Pediatric Cohort of Hospitalized Patients
Endreffy I, Bjørklund G, Szerafin L, Urbina MA, Chirumbolo S, Endreffy E
Immunologic Research 2017;65:1025–1030. PubMed PMID: 28808940 (IF 2.905)

Predictive Value of Selected Biomarkers Related to Metabolism and Oxidative Stress in Children with Autism Spectrum Disorder
El-Ansary A, Bjørklund G, Chirumbolo S, Alnakhli OM
Metab Brain Dis 2017;32:1209-1221. PubMed PMID: 28497358 (IF 2.603) 

Pyrethroid Pesticides in the Autophagy/Apoptosis Balance: Role in Adipocyte Lipidogenesis
Chirumbolo S, Bjørklund G
Food Chem Toxicol 2017;106:568-569. PubMed PMID: 28377267 (IF 3.584)

Recent Aspects of Uranium Toxicology in Medical Geology
Bjørklund G, Christophersen OA, Chirumbolo S, Selinus S, Aaseth J
Environ Res 2017;156:526-533. PubMed PMID: 28431380 (IF 3.835)

Relationship between Selenium, Lead, and Mercury in Red Blood Cells of Saudi Autistic Children 
El-Ansary A, Bjørklund G, Tinkov AA, Skalny A, Al Dera HS
Metab Brain Dis. 2017;32:1073-1080. PubMed PMID: 28326463 (IF 2.603)

Role of Oxidative Stress and Antioxidants in Daily Nutrition and Human Health
Bjørklund G, Chirumbolo S
Nutrition 2017;33:311-321. PubMed PMID: 27746034 (IF 2.839)

The Antinociceptive Activity of Geraniol
Chirumbolo S, Bjørklund G
Basic Clin Pharmacol Toxicol 2017;120:105-107. PubMed PMID: 28000392 (IF 3.097)

The Breakthroughs of Karl Folkers in Biochemistry and Human Nutrition
Bjørklund G, Chartrand M
J Nutr Disorders Ther 2017;7:2. doi: 10.4172/2161-0509.1000213

The Role of Cadmium in Obesity and Diabetes
Tinkov AA, Filippini T, Ajsuvakova OP, Aaseth J, Gluhcheva YG, Ivanova JM, Bjørklund G, Skalnaya MG, Gatiatulina ER, Popova EV, Nemereshina ON, Vinceti M, Skalny AV
Sci Total Environ 2017;601–602:741–755. PubMed PMID: 28577409 (IF 3.976)

The Role of Vitamin D in the Immune System as a Pro-survival Molecule 
Chirumbolo S, Bjørklund G, Sboarina A, Vella A
Clinical Therapeutics 2017;39:894-916. PubMed PMID: 28438353 (IF 2.925)

The Sesquiterpene α-bisabolol in the Adipocyte-cancer Desmoplastic Crosstalk: does it have an Action on Epithelial-mesenchymal Transition Mechanisms?
Chirumbolo S, Bjørklund G
Int J Clin Oncol 2017;22:222–228. PubMed PMID: 27942879 (IF 1.806)

The Toxicology of Mercury: Current Research and Emerging Trends
Bjørklund G, Dadar M, Mutter J, Aaseth J
Environ Res 2017;159:545-554. PubMed PMID: 28889024 (IF 3.835)

Tryptophan Status in Autism Spectrum Disorder and the Influence of Supplementation on Its Level
Kałużna-Czaplińska J, Jóźwik-Pruska J, Chirumbolo S, Bjørklund G
Metab Brain Dis 2017;32:1585-1593. PubMed PMID: 28608247 (IF 2.297)

Using a CD45dim/CD123bright/HLA-DRneg phenotyping protocol to gate basophils in FC for airway allergy. CD123 does not decrease
Chirumbolo S, Bjørklund G, Vella A
Adv Respir Med 2017;85:193-201. PubMed PMID: 28871586      

Vaccination is Fundamental but Can It Escape from a More Insightful and Critical Information about Its Action? 
Chirumbolo S, Bjørklund G
Environ Toxicol Pharmacol 2017;55:8–13. PubMed PMID: 28800561 (IF 2.313)


Publications 2016


Acid Glycosaminoglycan (aGAG) Excretion is increased in Children with Autism Spectrum Disorder, and it can be controlled by Diet
Endreffy I, Bjørklund G, Dicső F, Urbina MA, Endreffy E
Metab Brain Dis 2016;31:273-278. PubMed PMID: 26464064 – ResearchGate (IF 2.603)

Altered Urinary Porphyrins and Mercury Exposure as Biomarkers for Autism Severity in Egyptian Children with Autism Spectrum Disorder
Khaled EM, Meguid NA, Bjørklund G, Gouda A, Bahary MH, Hashish A, Sallam NM, Chirumbolo S, El-Bana MA
Metab Brain Dis 2016;31:1419-1426. PubMed PMID: 27406246 (IF 2.603)

Can Wnt5a and Wnt Non-Canonical Pathways Really Mediate Adipocyte Dedifferentiation in a Tumor Microenvironment?
Chirumbolo S, Bjørklund G
Eur J Cancer 2016;64:96-100. PubMed PMID: 27391920 (IF 6.163)

Commentary: Arnica Montana Effects on Gene Expression in a Human Macrophage Cell Line. Evaluation by Quantitative Real-Time PCR
Chirumbolo S, Bjørklund G
Front Immunol 2016;7:280. PubMed PMID: 27660630 (IF 5.695)

Commentary: Sulfur Dioxide Contributes to the Cardiac and Mitochondrial Dysfunction in Rats
Chirumbolo S, Bjørklund G
Front Cardiovasc Med 2016;3:15. doi:10.3389/fcvm.2016.00015

Commentary: The Flavonoid Baicalein Rescues Synaptic Plasticity and Memory Deficits in a Mouse Model of Alzheimer’s Disease
Chirumbolo S, Bjørklund G
Front Neurol 2016;7:141. doi:10.3389/fneur.2016.00141. PMID: 27618870

Evaluation of Whole Blood Zinc and Copper Levels in Children with Autism Spectrum Disorder
Crăciun EC, Bjørklund G, Tinkov AA, Urbina MA, Skalny AV, Rad F, Dronca E
Metab Brain Dis 2016;31:887-890. PubMed PMID: 27059237 (IF 2.603)

Immune Dysfunction and Neuroinflammation in Autism Spectrum Disorder
Bjørklund G, Saad K, Chirumbolo S, Kern JK, Geier DA, Geier MR, Urbina MA
Acta Neurobiol Exp (Wars) 2016;76:257-268. PubMed PMID: 28094817 (IF 1.708)

Mental and Spiritual Health and the Heart: A Viewpoint
Singh RB, Bjørklund G, Shastun S, Cornelissen G, Elkilany G, Agnieszka Wilczynska, De Meester F, Hristova K
World Heart J 2016;8:233-236. ResearchGate

Mercury as a Possible Link Between Maternal Obesity and Autism Spectrum Disorder
Skalny AV, Skalnaya MG, Bjørklund G, Nikonorov AA, Tinkov AA
Med Hypotheses 2016;91:90-94. PubMed PMID: 27142153 – ResearchGate (IF 1.136)

Nutritional and Environmental Influences on Autism Spectrum Disorder
Bjørklund G, Chartrand M
J Nutr Disorders The 2016;6(1):e123. doi:10.4172/2161-0509.1000e123

Red Seaweeds for Obesity Prevention?
Chirumbolo S, Bjørklund G
Food Chem Toxicol 2016; 94: 268-269 (IF 3.584)

Resveratrol and Cisplatin in a Malignant Mesothelioma Cell Model
Chirumbolo S, Bjørklund G
Food Chem Toxicol 2016;98(Pt B):308-309. PMID: 27856297 (IF 3.584)

The Levels of Blood Mercury and Inflammatory-related Neuropeptides in the Serum are correlated in Children with Autism Spectrum Disorder
Mostafa GA, Bjørklund G, Urbina MA, AL-Ayadhi LY
Metab Brain Dis 2016;31:593-599. PubMed PMID: 26738726ResearchGate (IF 2.603)

The Positive Association between Elevated Blood Lead Levels and Brain-specific Autoantibodies in Autistic Children from Low Lead-polluted Areas
Mostafa GA, Bjørklund G, Urbina MA, Al-Ayadhi LY
Metab Brain Dis 2016;31:1047-1054. PMID: 27250967 (IF 2.603)

Treatment Strategies in Alzheimer´s Disease: A Review with Focus on Selenium Supplementation 
Aaseth J, Alexander J, Bjørklund G, Hestad K, Dusek P, Roos PM, Alehagen U
Bometals 2016;29:827-839. PMID: 27530256 (IF 2.134)

Vitamin D Deficiency: A Global Health Problem
Bjørklund G
Peertechz J Environ Sci Toxicol 2016;1(1):023-024

Vitamin D Status in Autism Spectrum Disorders and the Efficacy of Vitamin D Supplementation in Autistic Children
Saad K, Abdel-rahman AA, Elserogy YM, Al-Atram AA, Cannell JJ, Bjørklund G, Abdel-Reheim MK, Othman HAK, El-Houfey AA, Hashem EA, Abd El-Aziz NHR, Abd El-Baseer KA, Ahmed AE, Ali AM
Nutr Neurosci 2016;19:346-351. PubMed PMID: 25876214 (IF 2.616)


Publications 2015


A Randomized, Placebo-Controlled Trial of Digestive Enzymes in Children with Autism Spectrum Disorders
Saad K, Eltayeb AA, Mohamad IL, Al-Atram AA, Elserogy Y, Bjørklund G, El-Houfey AA, Nicholson B
Clin Psychopharmacol Neurosci 2015;13:188-193. PubMed PMID: 26243847 – ResearchGate (IF 1.500)

ADHD, Autism and Neuroradiological Complications among Phenylketonuric Children in Upper Egypt
Saad K, Elserogy Y, Abdel Rahman AA, Al-Atram AA, Mohamad IL, ElMelegy TTH, Bjørklund G, El-Houfy AA
Acta Neurol Belg. 2015;115:657-663. PubMed PMID: 25576444 – ResearchGate (IF 1.495)

Clinical Use of the Metal Chelators Calcium Disodium Edetate, DMPS, and DMSA
Bjørklund G
Saudi J Kidney Dis Transpl 2015;26:611-612. PubMed PMID: 26022042

Diet and Atherosclerosis in Ancient Periods
Bjørklund G, Wilson DW, De Meester F, Takahashi T, Wilczynska A, Singh RB, Saboo B
World Heart J 2015;7(1):51-61

Increased Frequency of Delayed Type Hypersensitivity to Metals in Patients with Connective Tissue Disease
Stejskal V, Reynolds T, Bjørklund G
J Trace Elem Med Biol 2015;31:230–236. PubMed PMID: 25636536 (IF 2.550)

Levels of Metals in the Blood and Specific Porphyrins in the Urine in Children with Autism Spectrum Disorders
Macedoni-Lukšič M, Gosar D, Bjørklund G, Oražem J, Kodrič J, Lešnik-Musek P, Zupančič M, France-Štiglic A, Sešek-Briški A, Neubauer D, Osredkar J
Biol Trace Elem Res 2015;163:2-10. PubMed PMID: 25234471 – ResearchGate (IF 1.798)

Selenium as an Antidote in the Treatment of Mercury Intoxication
Bjørklund G
Biometals. 2015;28:605-614. PubMed PMID: 25947386 (IF 2.134)

Systematic Assessment of Research on Autism Spectrum Disorder and Mercury Reveals Conflicts of Interest and the Need for Transparency in Autism Research
Kern JK, Geier DA, Deth RC, Sykes LK, Hooker BS, Love JM, Bjørklund G, Chaigneau CG, Haley BE, Geier MR
Sci Eng Ethics 2015. doi:10.1007/s11948-015-9713-6. PubMed PMID: 26507205 (IF 1.454)

The Adjuvant Nutritional Intervention in Cancer (ANICA) Trial
Bjørklund G
Nutr Cancer 2015;67:1355-1358. PubMed PMID: 26473998 (IF 2.241)

Vitamin D Deficiency and its Associated Predictors among Patients Visiting Primary Health Care Center
Kassab M, Alkhatib AJ, Shotar A, Bjørklund G
Res J Biol Sci 2015;10(4):78-80


Publications 2014


Depression among Addictive Patients in Jordan
Alkhatib AJ, Bashir NA, Bjørklund G, Shotar AM, Rawashdeh WS , AlOmary M, Al-kresha R
Indian Research Journal of Pharmacy and Science 2014;1(3):10-18

Evidence Supporting a Link Between Dental Amalgams in Chronic Illness, Fatigue, Depression, Anxiety, and Suicide
Kern JK, Geier DA, Bjørklund G, King PG, Homme KG, Haley BE, Sykes LK, Geier MR
Neuro Endocrinol Lett 2014;35:537-552. PubMed PMID: 25617876 (IF 0.82)

Serum Copper and Zinc Levels in Individuals with Autism Spectrum Disorders
Li SO, Wang JL, Bjørklund G, Zhao WN, Yin CH
Neuroreport 2014;25:1216–1220. PubMed PMID: 25162784 – ResearchGate (IF 1.343)

The Role of Heat Shock Protein 90 in Human Reproduction
Alkhatib AJ, Hamadneh J, Bjørklund G, Alrasheidi SA
Res J Biol Sci 2014;9:161-164


Publications 2013


Effect of Diet and Nutrients on Molecular Mechanism of Gene Expression Mediated by Nuclear Receptor and Epigenetic Modulation
Jalili M, Pati S, Rath B, Bjørklund G, Singh RB
Open Nutra J 2013;6:27-34

Metal-Induced Inflammation Triggers Fibromyalgia in Metal-Allergic Patients
Stejskal V, Öckert K, Bjørklund G
Neuro Endocrinol Lett 2013;34:559-565. PubMed PMID: 24378456 (IF 0.82)

The Role of Zinc and Copper in Autism Spectrum Disorders
Bjørklund G
Acta Neurobiol Exp 2013;73:225–236. PubMed PMID: 23823984 (IF 1.708)


RESEARCH
Manuscripts Submitted
Ongoing Projects